Genetic analyses of the QT interval and its components in over 250K individuals identifies new loci and pathways affecting ventricular depolarization and repolarization
William John Young, Najim Lahrouchi, Aaron J. Isaacs…·Antônio Luiz Pinho Ribeiro
Author
Tampere UniversityORCID 0000-0002-9345-9851Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
4 papers
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William John Young, Najim Lahrouchi, Aaron J. Isaacs…·Antônio Luiz Pinho Ribeiro
Ming‐Huei Chen, Laura M. Raffield, Abdou Mousas…·Ruth J. F. Loos
This study identifies 5,552 blood-cell trait-variant associations across 746,667 individuals from 5 global populations, including 71 novel loci and ancestry-specific variants not found in European ancestry populations.
Dragana Vuckovic, Erik L. Bao, Parsa Akbari…·Εvangelos Εvangelou
This study identifies 5,106 new genetic variants associated with blood cell traits using large-scale GWAS, highlighting the polygenic and monogenic basis of hematopoiesis.
Ιωάννα Ντάλλα, Lu-Chen C Weng, James Cartwright…·Dan M. Roden
This study identifies 210 genetic loci associated with the PR interval through multi-ancestry GWAS, highlighting their role in cardiac conduction and cardiovascular disease.