MarkovHC: Markov hierarchical clustering for the topological structure of high-dimensional single-cell omics data
Zhenyi Wang, Yanjie Zhong, Zhaofeng Ye, Lang Zeng, Yang Chen, Minglei Shi, Minping Qian, Michael Q. Zhang
MarkovHC is a clustering algorithm that identifies cell types, trajectories, and critical points in single-cell omics data by reconstructing a pseudo-energy landscape based on metastability theory.
bioRxiv · Nov 4, 2020 · PreprintBioinformatics