Author

Joao Carlos Seco

German Cancer Research CenterORCID 0000-0002-9458-2202Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrey Tkachenko· 1 shared Christina StengliD· 1 shared Constantin SchorlingiD· 1 shared Evelyn RauthiD· 1 shared Luca TirinatoiD· 1 shared Maria Francesca SpadeaiD· 1 shared Mark Daniel ArndtiD· 1 shared Rico HansleriD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Andrey Tkachenko

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2 papers

Recent·Most cited

Correlation of OCT-Based Radiomic Signatures With Dose-Associated Radiation Response in Tumor Spheroids

Mark Daniel Arndt, Rico Hansler, Luca Tirinato, Andrey Tkachenko, Joao Carlos Seco, Werner Nahm, Ute Schepers, Maria Francesca Spadea

This paper evaluates OCT radiomics for quantifying radiation response in tumor spheroids, finding OCT-only models outperform brightfield imaging in dose prediction.

bioRxiv · Jul 9, 2026 · PreprintCancer Biology

Experimental investigation of oxygen diffusion in the peak and valley region of minibeam patterns during X-Ray irradiation

Constantin Schorling, Evelyn Rauth, Christina Stengl, Joao Carlos Seco

This study experimentally investigates oxygen depletion and diffusion in minibeam irradiation, finding higher depletion rates in valley regions and diffusion between peaks and valleys.

Medical Physics · Aug 1, 2025Peer-reviewedBiochemistry