Synthetic torpor triggers a neuroprotective and regulated mechanism in the rat brain, favoring the reversibility of Tau protein hyperphosphorylation.
Fabio Squarcio, Timna Hitrec, Emiliana Piscitiello, Matteo Cerri, Catia Giovannini, Davide Martelli, Alessandra Occhinegro, Ludovico Taddei, Domenico Tupone, Roberto Amici, Marco Luppi
The paper investigates how synthetic torpor induces reversible Tau hyperphosphorylation in rats, revealing a regulated neuroprotective mechanism involving metabolic and inflammatory changes.
Frontiers in Physiology · Mar 9, 2023Peer-reviewedNeuroscience