Investigating an in-silico approach for prioritizing antidepressant drug prescription based on drug-induced expression profiles and predicted gene expression
Muhammad Shoaib, Edoardo Giacopuzzi, Oliver Pain, Chiara Fabbri, Chiara Magri, Alessandra Minelli, Cathryn M. Lewis, Massimo Gennarelli
This paper ranks antidepressants based on their similarity to gene expression profiles of treatment responders, finding escitalopram and citalopram show high rankings in some cell lines.
The Pharmacogenomics Journal · Sep 17, 2020Peer-reviewedBioinformatics