Ahmet Can Timuçin

This study benchmarks AlphaFold2 and OpenFold3 on protein-peptide complexes, finding AlphaFold2 outperforms OpenFold3 in success rate and high-quality model proportion.

This study presents near-physiological structures of the Fc fragment from a biosimilar VEGF-Trap and shows structural plasticity through molecular dynamics simulations.

This study identifies biases in protein stability datasets caused by concentrated neutral mutations and proposes under-sampling to balance ΔΔG distributions, improving predictor performance.