Neuroimaging-AI endophenotypes reveal underlying mechanisms and genetic factors contributing to progression and development of four brain disorders
Junhao Wen, Ioanna Skampardoni, Ye Tian, Zhijian Yang, Yuhan Cui, Güray Erus, Gyujoon Hwang, Erdem Varol, Aleix Boquet-Pujadas, Ganesh B. Chand, Ilya M. Nasrallah, Theodore Daniel Satterthwaite, Haochang Shou, Li Shen, Arthur W. Toga, , Christos A. Davatzikos
The paper identifies nine neuroimaging endophenotypes linked to genetic loci and shows they improve prediction of systemic diseases and mortality.
Nature Biomedical Engineering · Jun 6, 2025Peer-reviewedGenetic & Genomic Medicine