Author
Evgenij Fiškin
Broad InstituteORCID 0000-0002-9510-0826Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2020-2023 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 41 mutual co-author links4 papers
Recent·Most cited
- GeneticsbioRxivPreprint
Single-cell multi-omics reveals dynamics of purifying selection of pathogenic mitochondrial DNA across human immune cells
Caleb A. Lareau, Sonia M. Dubois, Frank A. Buquicchio…·Leif S. Ludwig
The paper uses single-cell multi-omics to study how pathogenic mtDNA mutations are subject to purifying selection in immune cells from Pearson syndrome patients.
- GenomicsbioRxivPreprint
Single-cell multimodal profiling of proteins and chromatin accessibility using PHAGE-ATAC
Evgenij Fiškin, Caleb A. Lareau, Gökçen Eraslan…·Aviv Regev
The paper introduces PHAGE-ATAC, a method for simultaneous single-cell measurement of surface proteins, chromatin accessibility, and mtDNA-based clonal tracing, and demonstrates its application in human immune cells.
11 citations - BioinformaticsbioRxivPreprint✦ In-depth digest
Integrated analyses of single-cell atlases reveal age, gender, and smoking status associations with cell type-specific expression of mediators of SARS-CoV-2 viral entry and highlights inflammatory programs in putative target cells
Christoph Muus, Malte D. Luecken, Gökçen Eraslan…·Wenjun Yan
Across 1,176,683 airway and lung cells from 22 datasets, ACE2 rises with age, in males and in smokers' multiciliated cells, and is lowest in young children.