Author

Quentin Mark Anstee

Newcastle UniversityORCID 0000-0002-9518-0088Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genetic & Genomic Medicine· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:dimensionality reduction· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Assay:proteomics· 1

Frequent Co-Authors

Adam E. LockeiD· 1 shared Adrienne A. UnsworthiD· 1 shared Alexis ComberiD· 1 shared Amit V. KheraiD· 1 shared Anastasia ResteuiD· 1 shared Andrew D. WellsiD· 1 shared Ann K. DalyiD· 1 shared Anna Vathrakokoili PournaraiD· 1 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Adam E. LockeORCID

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Author profile →

3 papers

Recent·Most cited

BioinformaticsbioRxivPreprintJan 17, 2025

STExplorer: Navigating the Micro-Geography of Spatial Omics Data

Eleftherios Zormpas, Nikolaos I. Vlachogiannis, Anastasia Resteu…·Simon Cockell

STExplorer applies computational geography methods to spatial transcriptomics data to uncover spatially resolved patterns and heterogeneity.

1 citation

spatial transcriptomicsstatistical model

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Systems BiologybioRxivPreprintJan 14, 2025

Decoding MASLD Progression: A Molecular Trajectory-Based Framework for Modelling Disease Dynamics

Ioannis Kamzolas, Thodoris Koutsandreas, Charlie George Barker…·Evangelia Petsalaki

This paper develops a molecular trajectory-based framework to model MASLD progression using transcriptomic and proteomic data, identifying novel biomarkers and mechanistic insights.

2 citations

humanbulk RNA-seq

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Genetic & Genomic MedicineNature GeneticsPeer-reviewedJun 1, 2022

A trans-ancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation.

Marijana Vujković, Shweta Ramdas, Kimberly Lorenz…·Kyong‐Mi Chang

This study conducts a trans-ancestry GWAS using chronic ALT elevation as a proxy for NAFLD, identifies 77 significant loci, and validates 17 SNPs with histology and imaging data, revealing genetic links to metabolic and inflammatory traits.

205 citationstop 1%

humanGWAS summary statistics

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