Author

Vito Alessandro Lasorsa

CEINGE Biotecnologie Avanzate Franco Salvatore (Italy)ORCID 0000-0002-9552-7192Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:GWAS / association mapping· 2 Assay:GWAS summary statistics· 2 Approach:statistical model· 2 Approach:experimental assay· 1

Frequent Co-Authors

Achille IolasconiD· 3 shared Immacolata AndolfoiD· 3 shared Mario CapassoiD· 3 shared Roberta RussoiD· 3 shared Biancamaria PierriiD· 2 shared Massimo ZolloiD· 2 shared Pellegrino CerinoiD· 2 shared Sueva CantalupoiD· 2 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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3 shared papersGenetic & Genomic Medicine

Achille IolasconORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Targeting ATP2B1 impairs PI3K/Akt/Fox-O3 signaling and reduces SARS-COV-2 replication in vivo.

Pasqualino De Antonellis, Veronica Ferrucci, Francesca Bibbò, Fathem Asadzadeh, Francesca Gorini, Angelo Sabato Boccia, Carmen Sorice, Roberto Siciliano, Roberta Russo, Immacolata Andolfo, Vito Alessandro Lasorsa, Sueva Cantalupo, Giovanni Paolella, Giovanna Fusco, Maurizio Viscardi, , Massimo Zollo

This study shows that inhibiting ATP2B1 with compound PI-7 reduces SARS-CoV-2 replication by lowering intracellular calcium levels and disrupting the PI3K/Akt/FoxO3 signaling pathway.

medRxiv · Sep 2, 2022 · PreprintGenetic & Genomic Medicine

Common variants at 21q22.3 locus influence MX1 gene expression and susceptibility to severe COVID-19

Immacolata Andolfo, Roberta Russo, Vito Alessandro Lasorsa, Sueva Cantalupo, Barbara Eleni Rosato, Ferdinando Bonfiglio, Giulia Frisso, Pasquale Abete, Gian Marco Cassese, Giuseppe Servillo, Gabriella Esposito, Ivan Gentile, Carmelo Piscopo, Romolo Villani, Giuseppe Fiorentino, , Mario Capasso

The paper identifies common variants near the MX1 gene associated with reduced risk of severe COVID-19 and increased MX1 expression.

iScience · Mar 18, 2021Peer-reviewedGenetic & Genomic Medicine

Genetic analysis of the novel SARS-CoV-2 host receptor TMPRSS2 in different populations.

Roberta Russo, Immacolata Andolfo, Vito Alessandro Lasorsa, Achille Iolascon, Mario Capasso

The paper analyzes TMPRSS2 coding-region and eQTL variants across populations to assess their impact on susceptibility to SARS-CoV-2 infection.

bioRxiv · Apr 23, 2020 · PreprintGenetics