BioinformaticsbioRxivPreprint
Analysis of single-cell RNA-seq data from ovarian cancer samples before and after chemotherapy links stress-related transcriptional profile withchemotherapy resistance
Kaiyang Zhang, Erdoğan Pekcan Erkan, Jun Dai…·Anna Vähärautio
The paper identifies a stress-related transcriptional profile in ovarian cancer linked to chemotherapy resistance and poor survival, suggesting MEK1/2 inhibitors as a potential treatment.