PhISCS-BnB: A Fast Branch and Bound Algorithm for the Perfect Tumor Phylogeny Reconstruction Problem
Erfan Sadeqi Azer, Farid Rashidi Mehrabadi, Salem Malikić, Xuan Cindy Li, Osnat Bartok, Kevin Litchfield, Ronen Levy, Yardena Samuels, Alejandro A. Schäffer, Edward Michael Gertz, Chi‐Ping Day, Eva Pérez‐Guijarro, Kerrie L. Marie, Maxwell P. Lee, Glenn T Merlino, , S. Cenk Şahinalp
PhISCS-BnB computes the most likely perfect tumor phylogeny from single-cell sequencing data, offering optimality guarantees and significant speed improvements over existing methods.
Bioinformatics · Jul 1, 2020Peer-reviewedBioinformatics