Targeting Plasmodium falciparum calcium dependent protein kinase-1: Computational modelling approach towards the discovery of antimalarial drug from medicinal herbs and clinically approved anti-malarial drugs pharmacophores
Temitope Isaac Adelusi, Taiwo Ooreoluwa Ojo, Olawale Quadri Bolaji, Moyosoluwa Precious Oyewole, Elijah Kolawole Oladipo
This paper identifies 88 compounds that inhibit PfCDPK1, with 12 showing particularly strong binding affinities, using computational methods on antimalarial drug pharmacophores.
bioRxiv · Aug 22, 2022 · PreprintBioinformatics