Author

Jorge E. Buendia-Buendia

Broad InstituteORCID 0000-0002-9675-6827Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

D. Kim· 1 shared Eric P. WineriD· 1 shared Esha JainiD· 1 shared Nikhil WagleiD· 1 shared NU LiniD· 1 shared Ofir CoheniD· 1 shared Romualdo Barroso‐SousaiD· 1 shared Sara M. TolaneyiD· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperGenomics

D. Kim

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1 paper

Recent·Most cited

Prevalence and mutational determinants of high tumor mutation burden in breast cancer

Romualdo Barroso‐Sousa, Esha Jain, Ofir Cohen, D. Kim, Jorge E. Buendia-Buendia, Eric P. Winer, NU Lin, Sara M. Tolaney, Nikhil Wagle

This study finds that 5% of breast cancers have high tumor mutation burden, more common in metastatic tumors, with APOBEC activity as the most common mutational process and potential benefit from PD-1 inhibitors.

Annals of Oncology · Jan 9, 2020Peer-reviewedGenomics