Author

Marie Goret

Centre National de la Recherche ScientifiqueORCID 0000-0002-9686-5476Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

Jocelyn LaporteiD· 2 shared Gwenaelle Piccolo· 1 shared Thomas Arbogast· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

3 top collaborators · 2 mutual co-author links

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2 shared papersNeuroscience

Jocelyn LaporteORCID

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2 papers

Recent·Most cited

Muscle-specific DNM2 overexpression improves Charcot-Marie-Tooth disease in vivo and reveals a narrow therapeutic window in skeletal muscle

Marie Goret, Gwenaelle Piccolo, Jocelyn Laporte

This study shows that muscle-specific DNM2 overexpression improves CMT symptoms in mice, but systemic delivery worsens muscle pathology, highlighting a narrow therapeutic window for DNM2 modulation.

International Journal of Molecular Sciences · Feb 2, 2026Peer-reviewedNeuroscience

DNM2-CMT neuropathy stems from disrupted Schwann cell function and shows limited therapeutic reversibility

Marie Goret, Thomas Arbogast, Jocelyn Laporte

This study characterizes a Dnm2K562E/SC- mouse model of DNM2-CMT, showing axonal loss, demyelination, and limited therapeutic response to DNM2 supplementation.

bioRxiv · Dec 4, 2025 · PreprintNeuroscience