Author

Jiawei Shen

Washington University in St. LouisORCID 0000-0002-9728-2352Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Approach:machine learning (classical)· 1 Approach:statistical model· 1

Frequent Co-Authors

Daofeng LiiD· 2 shared Juan F. Macias-VelascoiD· 2 shared Qichen FuiD· 2 shared Ting WangiD· 2 shared Andrew RuttenbergiD· 1 shared Benjamin K. JohnsoniD· 1 shared Benpeng MiaoiD· 1 shared Chad TomlinsoniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenomics

Daofeng LiORCID

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintJul 26, 2026

Pansoma, a machine learning tool for identifying somatic variants using pangenome graphs

Jiawei Shen, Qichen Fu, Juan F. Macias-Velasco…·Ting Wang

Pansoma improves somatic variant calling using pangenome graphs, enhancing accuracy by avoiding reference bias and preserving graph-specific variant representations.

DOI 10.64898/2026.05.27.726245

humanwhole-genome sequencing

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GenomicsbioRxivPreprintJan 5, 2026

Leveraging Human Pangenome for Improved Somatic Variant Detection

Qichen Fu, Zilan Xin, Benpeng Miao…·Ting Wang

This study shows that using graph-based pangenomes and inferred donor-specific assemblies improves somatic variant detection compared to GRCh38.

DOI 10.64898/2026.01.04.697580

humanwhole-genome sequencing

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