Simon K.‐M. R. Rittmann

Pilot-scale production of leucine from CO2

This paper reports the first archaeal cell factory for leucine production from CO2, achieving high productivity and economic feasibility in a pilot-scale bioprocess.

CFD-Informed Hybrid Modeling Unlocks Scalable, Tunable Amino Acid Production in Methanothermobacter marburgensis

This study develops a hybrid modeling approach to scale up amino acid production in Methanothermobacter marburgensis using CFD and DOE techniques.

Valine overproduction with metabolically engineered Methanothermobacter marburgensis

This paper demonstrates enhanced valine production in Methanothermobacter marburgensis using genetic engineering and promoter systems, achieving high specific productivity.