TRPM2 is a direct pain transducer
Linda Varghese, Mujahid Alizada, Jinquan Yang, Feng Ye, Xiaoqiu Yuan, Mitali Malhotra, Xuming Zhang
This study identifies neuronal TRPM2 as a direct pain transducer that mediates acute and chronic pain independently of immune TRPM2 and inflammation.
Proceedings of the National Academy of Sciences · Sep 16, 2026Peer-reviewedNeuroscience