Whole genome analysis of plasma fibrinogen reveals population-differentiated genetic regulators with putative liver roles.
Jennifer E. Huffman, Jayna C. Nicholas, Julie M. Hahn, Adam S. Heath, Laura M. Raffield, Lisa R. Yanek, Jennifer A. Brody, Florian Thibord, Laura A. Almasy, Traci M. Bartz, Lawrence F. Bielak, Russell Paul Bowler, Germán D. Carrasquilla, Daniel I. Chasman, Ming‐Huei Chen, , Yoav Ben‐Shlomo
This study uses whole genome sequencing to identify 18 novel genetic loci associated with plasma fibrinogen levels, including variants more common in African populations and linked to liver-related traits and disease.
Blood · Sep 3, 2024Peer-reviewedGenetic & Genomic Medicine