Author
Washington University in St. LouisORCID 0000-0002-0933-2410Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
13 papers
Recent·Most cited
H. Wang, Pavithra Nagarajan, Clint L. Miller…·Caroline Hayward
The paper identifies 16 genetic loci interacting with sleep duration to influence glycemic traits in over 480,000 individuals, revealing distinct biological mechanisms for short and long sleep.
Mengze Li, Zeyuan Song, Eric R. Reed…·Stefano Monti
This study identifies age and survival-related transcriptomic signatures in longevity-enriched cohorts using RNAseq data from blood samples.
Mengyu Zhang, Michael R. Brown, Amy R. Bentley…·Bertha Hidalgo
This study identifies twelve novel blood pressure loci and shows smoking modifies genetic effects on BP through immune-related pathways in over 1 million individuals.
Raymond Noordam, Wenyi Wang, Pavithra Nagarajan…·Rima Destya Triatin
This study identifies 17 genetic loci associated with sleep duration and lipid levels, offering potential druggable targets for dyslipidemia in individuals with sleep disturbances.
Mary Furlan Feitosa, Shiow J. Lin, Sandeep Acharya…·Michael A. Province
The paper identifies pleiotropic genetic factors shared between kidney function and sRAGE using GWAS and TWAS in the LLFS cohort.
Sandeep Acharya, Shu Liao, Wooseok J. Jung…·Michael R. Brent
The paper integrates multi-omics data to identify genes influencing cardiovascular risk traits in the Long Life Family Study, finding 64 significant genes and replicating 29 in the Framingham Heart Study.
Sophia Gunn, Michael Wainberg, Zeyuan Song…·Paola Sebastiani B
The paper evaluates 54 polygenic risk scores in long-lived individuals and their offspring, finding lower genetic risk for Alzheimer's, CAD, and lupus, but not for dementia in long-lived individuals.
Julie M. Hahn, Yi‐Ping Fu, Michael R. Brown…·Alanna C. Morrison
This study identifies new genetic loci associated with myocardial infarction and coronary heart disease using genome-wide association analyses across multiple cohorts.
Vincent Laville, Timothy D. Majarian, Paul S. de Vries…·on behalf of the CHARGE Gene-Lifestyle Interactions Working Group
This paper develops a method to estimate stratified and marginal summary statistics from a joint gene-environment interaction model, demonstrating its accuracy through simulations and real data applications.
Vincent Laville, Timothy D. Majarian, Yun Ju Sung…·on behalf of the CHARGE Gene-Lifestyle Interactions Working Group
The paper analyzes gene-environment interaction effects across multiple ancestries and traits, identifying population-specific genetic mechanisms and methodological biases in GxE studies.
Raymond Noordam, Maxime M. Bos, Heming Wang…·André Gerardus Uitterlinden
The paper identifies 49 novel blood lipid loci associated with gene-sleep interactions in 126,926 individuals across 5 ancestry groups, with gene-short-sleep interactions explaining 4.25% of triglyceride variance.
Anne E. Justice, Tugce Karaderi, Heather M. Highland…·Andrew Tym Hattersley
This study identifies 15 common and 9 low-frequency protein-coding variants associated with body fat distribution, implicating novel genes related to lipid homeostasis and type 2 diabetes.
Annah B. Wyss, Tamar Sofer, Mi Kyeong Lee…·Josée Dupuis
This study identifies over 50 new genetic loci associated with pulmonary function through a multiethnic meta-analysis of 90,715 individuals.