Liver single-nucleus multiome profiling reveals cell-type mechanisms for cardiometabolic traits
Abdalla A Alkhawaja, Kevin W. Currin, Hannah J. Perrin, Swarooparani Vadlamudi, Amy S. Etheridge, K. Alaine Broadaway, Gabrielle Heather Cannon, Carlton W. Anderson, Anne H. Moxley, Alina Cornelia Iuga, Erin G. Schuetz, F. Innocenti, Terrence S. Furey, Karen L. Mohlke
The paper uses single-nucleus multiome sequencing to identify cell-type-specific regulatory mechanisms for cardiometabolic traits by integrating QTLs and GWAS signals.
The American Journal of Human Genetics · Dec 2, 2025Peer-reviewedGenomics