K. Alaine Broadaway

The paper shows larger eQTL studies detect more signals that colocalize with GWAS signals, improving understanding of gene-trait relationships.

The paper uses single-nucleus multiome sequencing to identify cell-type-specific regulatory mechanisms for cardiometabolic traits by integrating QTLs and GWAS signals.

The paper identifies additional eQTL signals in adipose tissue and shows they contribute to cardiometabolic traits through gene dosage effects.

This study identifies 1,289 genetic signals for type 2 diabetes in 2.5 million individuals, revealing distinct clusters linked to vascular complications and highlighting ancestry-specific genetic risk factors.

The paper identifies context-specific genetic effects on gene regulation in neural progenitors by stimulating the Wnt pathway and analyzing chromatin accessibility and gene expression.

This paper introduces a method to improve genetic association testing for psychiatric symptoms by analyzing multivariate questionnaire data instead of collapsing it into a single score, showing increased power and efficiency.