Author

Jianhua Wang

Mayo ClinicORCID 0000-0002-9795-9765Unclaimed ORCID profile · follow to get notified of new preprints

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Jianhua Wang3 papers · Shanghai Medical College of Fudan University

Biology Disciplines

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Bioinformatics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:benchmarking· 1 Assay:ChIP-seq· 1 Research Focus:database / resource· 1 Approach:deep learning· 1 Research Focus:fine-mapping· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Dandan HuangiD· 2 shared Hongcheng YaoiD· 2 shared Ke ZhaoiD· 2 shared Kexin CheniD· 2 shared Mulin Jun LiiD· 2 shared Pak Chung ShamiD· 2 shared Xianfu YiiD· 2 shared Xiaobao DongiD· 2 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioinformatics

Dandan HuangORCID

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2 papers

Recent·Most cited

Inferring CTCF binding patterns and anchored loops across human tissues and cell types

Hang Xu, Xianfu Yi, Xutong Fan, Chengyue Wu, Wei Wang, Xinlei Chu, Shijie Zhang, Xiaobao Dong, Zhao Wang, Jianhua Wang, Yao Zhou, Ke Zhao, Hongcheng Yao, Nan Zheng, Junwen Wang, , Mulin Jun Li

The paper develops DeepAnchor, a deep learning model to characterize CTCF binding patterns and predict CTCF-anchored loops across human tissues, revealing sequence and chromatin features that influence loop formation and disease mechanisms.

Patterns · Jul 12, 2023Peer-reviewedBioinformatics

Whole genome base-wise aggregation and functional prediction for human non-coding regulatory variants

Shijie Zhang, Yukun He, Huanhuan Liu, Haoyu Zhai, Dandan Huang, Xianfu Yi, Xiaobao Dong, Zhao Wang, Ke Zhao, Yao Zhou, Jianhua Wang, Hongcheng Yao, Hang Xu, Zhenglu Yang, Pak Chung Sham, , Mulin Jun Li

This paper develops regBase, a database of whole genome base-wise aggregations of regulatory variant predictions, and three composite models to score functional, pathogenic, and cancer driver variants, showing superior performance in fine-mapping causal variants.

Nucleic Acids Research · Aug 29, 2019Peer-reviewedGenomics