p38β/MAPK11 Deficiency Exacerbates Cardiac Structural and Electrophysiological Remodeling and Contributes to Immune Dysregulation in the Aging Heart
Katy Anne Trampel, Batool Salman, Lara Leoni, Sophie Green, Noor Saleem, Ava Adli, Daniele Procissi, Igor R. Efimov, Tatiana Efimova
This study shows that p38β deficiency worsens cardiac structure, electrophysiology, and immune function in aged mice, highlighting its protective role in aging hearts.
bioRxiv · Jun 23, 2026 · PreprintPhysiology