Author

Pedro Gonzalez‐Alegre

Spark Therapeutics (United States)ORCID 0000-0002-9887-2995Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Organism:rat· 1

Frequent Co-Authors

Alexandra J Gilsrud· 1 shared Apeksha Khatiwada· 1 shared Brittany Wicks· 1 shared Daniel Cohen· 1 shared Derek P. NarendraiD· 1 shared Elizabeth A. Ramsburg· 1 shared Eric Wildon KostukiD· 1 shared Maria Grazia BiferiiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Alexandra J Gilsrud

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1 paper

Recent·Most cited

Restoring Parkin Function: An AAV Gene Therapy Approach for Early-Onset Parkinson's Disease

Sambuddha Basu, Tyler G. Demarest, Nicholas J. Gattone, Alexandra J Gilsrud, Brittany Wicks, Apeksha Khatiwada, Mohammad Nayal, Renee C. Gentzel, Daniel Cohen, Eric Wildon Kostuk, Derek P. Narendra, Pedro Gonzalez‐Alegre, Maria Grazia Biferi, Elizabeth A. Ramsburg

This paper investigates AAV-mediated PRKN gene replacement in Parkin-deficient models to restore mitophagy and demonstrate a feasible gene therapy approach for early-onset Parkinson's disease.

bioRxiv · Jul 13, 2026 · PreprintNeuroscience