Vittoria Martinelli

Regulating population density through antithetic feedback control of cell growth

This paper introduces a genetic feedback control strategy for microorganisms to self-regulate population density using quorum sensing and an antithetic controller.

In silico analysis of metabolic burden effects on a multicellular integral controller

The paper models a multicellular antithetic integral controller to assess metabolic burden effects and compares it to a single-cell implementation using numerical analysis and simulations.

Root Contours Guided Design of a Multicellular PID Controller

The paper designs a multicellular PID controller using root contours for tuning control gains and validates it through in silico simulations.

Multicellular Proportional-Integral-Derivative Control for Robust Regulation of Biological Processes

The paper develops a multicellular PID control strategy using engineered cell populations and validates its robustness through in silico experiments.

Multicellular PD Control in Microbial Consortia

This paper designs a multicellular PD controller for gene expression regulation in microbial consortia using in silico experiments.

Multicellular PI control for gene regulation in microbial consortia

The paper designs multicellular PI controllers for gene regulation in microbial consortia using orthogonal quorum sensing and validates them through in silico experiments.