Author

Tyler T. Thaxton

Northwestern UniversityORCID 0000-0002-9901-7771Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Alexandra M HuffmaniD· 1 shared Alfred L. GeorgeiD· 1 shared Andrew D. NelsoniD· 1 shared Anna M. LipkiniD· 1 shared Cenfu WeiiD· 1 shared Christian HanseliD· 1 shared Christopher GomeziD· 1 shared Christopher H. ThompsoniD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Alexandra M HuffmanORCID

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2 papers

Recent·Most cited

Calcium channel-coupled transcription factors facilitate direct nuclear signaling

Eshaan R. Rao, Tyler T. Thaxton, Eric Gama, Jack D. Godfrey, Cenfu Wei, Qiaoshan Lin, Yan Li, Daniel Parviz Hejazi Pastor, Christian Hansel, Xiaofei Du, Christopher Gomez

The paper shows that VGCC C-terminal proteins regulate gene networks in neurons through Ca2+-dependent nuclear signaling.

bioRxiv · Feb 9, 2025 · PreprintNeuroscience

Cellular and behavioral effects of altered NaV1.2 sodium channel ion permeability in Scn2aK1422E mice

Dennis M. Echevarria-Cooper, Nicole A. Hawkins, Sunita N. Misra, Alexandra M Huffman, Tyler T. Thaxton, Christopher H. Thompson, Roy Ben‐Shalom, Andrew D. Nelson, Anna M. Lipkin, Alfred L. George, Kevin J. Bender, Jennifer A. Kearney

This paper investigates the effects of the SCN2A p.K1422E variant in mice, showing mixed functional and behavioral impacts on neurons and neurodevelopmental phenotypes.

Human Molecular Genetics · Apr 13, 2022Peer-reviewedNeuroscience