Emma X Liang

Metabolic complexity in the human brain supports metastable network dynamics and declines in normative ageing

This study investigates metabolic complexity in the human brain using PET and fMRI, finding that metabolic entropy correlates with network metastability and declines with age.

A Comparison of Brain Metabolic Connectivity Methods Topology, Cognition, Age, Structure, and Genetics

This paper compares brain metabolic connectivity methods using PET and fMRI data, finding that different approaches yield distinct topological, cognitive, structural, and genetic signatures, with fPET showing strongest cognitive associations and age-related declines.

Directed information flow across the metabolic network of the human brain

The paper uses fPET and Granger causality to analyze directed metabolic connectivity in brain circuits, finding that metabolic connections predict cognition and affect, and vary in efficiency and functional benefit.

Metabolic Connectivity Gradients of the Human Brain

This study identifies four metabolic connectivity gradients in the human brain, linking metabolic activity, cortical structure, and cognitive function across the lifespan.

Brain glucodynamic variability is an essential feature of the metabolism-cognition relationship

This study shows that variability in glucose metabolism, not just average rates, is linked to cognitive performance and metabolic network efficiency, with reduced variability in older adults associated with worse cognition.

Metabolic connectivity has greater predictive utility for age and cognition than functional connectivity.

This study compares metabolic and functional connectivity using fPET and fMRI to determine their predictive power for age and cognition, finding that metabolic connectivity is more predictive.

Peripheral insulin resistance attenuates cerebral glucose metabolism and impairs working memory in healthy adults

The paper investigates how peripheral insulin resistance affects cerebral glucose metabolism and working memory in healthy adults, finding greater impacts in younger adults.

Metabolic connectivity in ageing.

This study examines metabolic connectivity in ageing using high temporal resolution PET, finding reduced connectivity and altered topology in older adults linked to worse cognitive performance.

Multimodal, multiscale connectivity blueprints of the cerebral cortex

This paper integrates seven multimodal brain connectivity profiles to uncover universal organizational principles and maps them onto brain structure and function.

Metabolic and functional connectivity provide unique and complementary insights into cognition-connectome relationships

This study investigates how hemodynamic and metabolic brain connectivity relate to cognitive function using simultaneous FDG-fPET/fMRI and partial least squares analyses, revealing distinct cognitive associations for each modality.

Monash DaCRA fPET-fMRI: A DAtaset for Comparison of Radiotracer Administration for high temporal resolution functional FDG-PET

The paper introduces an open dataset comparing three FDG-fPET radiotracer administration protocols using simultaneous BOLD-fMRI scanning.

Metabolic and haemodynamic resting-state connectivity of the human brain: a high-temporal resolution simultaneous BOLD-fMRI and FDG-fPET multimodality study

This study uses simultaneous high-temporal resolution FDG-fPET and fMRI to compare metabolic and haemodynamic connectivity in the human brain, finding that metabolic connectivity is non-ergodic and differs from static FDG-PET covariance.