Linalool and trans-nerolidol prevent pentylenetetrazole-induced seizures in adult zebrafish
Adhemar Lourenço Da Silva, Leonardo M. Bastos, Matheus Gallas‐Lopes, Rafael Chitolina, Carlos G. Reis, Domingos Sávio Nunes, Elaine Elisabetsky, Ana Paula Herrmann, María Elisa Calcagnotto, Ângelo Piato
This study evaluates the antiseizure effects of linalool and trans-nerolidol in zebrafish using a PTZ-induced seizure model, finding that both compounds reduce seizure severity and delay progression, with trans-nerolidol showing stronger efficacy.
bioRxiv · Jan 14, 2025 · PreprintNeuroscience