Systems biology framework for rational design of operational conditions for in vitro / in vivo translation of microphysiological systems
Jose L. Cadavid, Nikolaos Meimetis, Tyler Matsuzaki, Erin N. Tevonian, Linda Gay Griffith, Douglas A. Lauffenburger
The paper develops a machine learning framework to identify optimal experimental conditions for improving the translatability of microphysiological systems to in vivo contexts, using MAFLD as a case study.
bioRxiv · Jan 17, 2025 · PreprintSystems Biology