Author

Mehdi Hicham

Swiss Cancer Center LémanORCID 0000-0002-9979-4757Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:deep learning· 1 Organism:mouse· 1 Assay:scRNA-seq· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Alan GuichardiD· 1 shared Celine Wyser-Rmili· 1 shared Florent DuvaliD· 1 shared Gaël BoiviniD· 1 shared João LourençoiD· 1 shared Michele De PalmaiD· 1 shared Nadine FournieriD· 1 shared Nahal MansouriiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperCancer Biology

Alan GuichardORCID

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1 paper

Recent·Most cited

The Immune Landscape of Tumor-Associated Macrophage Reprogramming

Florent Duval, João Lourenço, Mehdi Hicham, Gaël Boivin, Alan Guichard, Celine Wyser-Rmili, Nadine Fournier, Michele De Palma, Nahal Mansouri

This study uses single-cell RNA sequencing to show that Dicer1 deficiency in macrophages reprograms tumor-associated macrophages to an immunostimulatory state, enhancing antiangiogenic immunotherapy response in mouse models.

bioRxiv · Sep 25, 2024 · PreprintCancer Biology