Systems BiologyFrontiers in OncologyPeer-reviewed
Computational modeling of the crosstalk between macrophage polarization and tumor cell plasticity in the tumor microenvironment
Xuefei Li, Mohit Kumar Jolly, Jason Thomas George…·Herbert Levine
The paper uses computational models to study how macrophage polarization and cancer cell plasticity interact in the tumor microenvironment, showing that these interactions can lead to multiple stable states, including cancer cell extinction.
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