Development and qualification of an enzyme-linked immunosorbent assay to detect human serum immunoglobulin G reactive to multiple lineages of Lassa virus nucleoprotein
Heejin Yun, Faith Sigei, Nana Yaa Asiedua Appiah, Charlotte Naa Odey Quaye, Cecilia Adwoa Biaa Yankey, Eric Kyei Baafour, Peter Hayes, Arianna Marini, Robert T. Bailer, Marija Zaric, Kwadwo Asamoah Kusi
This paper develops and validates an ELISA to quantify anti-LASV-NP IgG in human serum, demonstrating sensitivity, precision, and specificity for LASV epidemiology and vaccine development.
PLoS ONE · Jul 2, 2026Peer-reviewedImmunology