BioinformaticsNature CommunicationsPeer-reviewed
Chromatin-informed inference of transcriptional programs in gynecologic and basal breast cancers
Hatice U. Osmanbeyoglu, Fumiko Shimizu, Ángela Rynne‐Vidal…·Christina S. Leslie
The paper develops PSIONIC, a machine learning method that integrates chromatin accessibility and RNA-seq data to infer transcriptional programs in gynecologic and basal breast cancers, revealing regulatory differences and survival associations.