Ekrem Yaşar

This paper benchmarks integrated cell-death prognostic signatures across cancers, finding they are biologically valid but not prognostically better than single-pathway models or proliferation markers.

This paper introduces a sonification framework for GPCR molecular dynamics and validates its ability to accurately represent activation states through cross-modal analysis.

This study uses molecular dynamics simulations to show Ang 1-7 stabilizes the inactive conformation of MasR and induces limited activation through non-canonical micro-switch dynamics.

This study investigates the structural and dynamic effects of the m.14849T>C variant in Cytochrome b, showing localized perturbations in the heme bL microenvironment that may contribute to multisystem mitochondrial disease.

This study uses molecular dynamics simulations to show how Ang II and Ang 1-7 ligands differentially affect AGTR2 activation by stabilizing or modulating receptor states through specific interactions.