Bernard Friedenson

The paper links transient viral infection to chronic diseases through epigenetic misprogramming in stem-cell differentiation pathways, identifying shared methylation signatures across diverse diseases.

This paper shows EBV infection reprograms the methylome of breast luminal progenitors to generate cancer stem-like cells, linking viral infection to early breast cancer development.

The paper identifies EBV-associated methylation patterns in breast cancer and normal tissues that align with stem cell differentiation pathways, suggesting EBV contributes to cancer susceptibility through epigenetic changes.

The paper shows EBV infections disable breast cancer safeguards, leading to similar genetic and molecular patterns as hereditary breast cancers.

The paper identifies herpes virus sequences near chromosome breaks in BRCA1/BRCA2 breast cancers, suggesting viral involvement in genomic instability.

This paper investigates the link between infections and chromosomal anomalies in neurodevelopmental disorders by analyzing microbial DNA and chromosomal deletions.

This study investigates how parental infections disrupt gene clusters involved in nervous system development, leading to chromosomal anomalies and neurodevelopmental disorders.