Víctor Andrade

The paper identifies HLA-A, HLA-B, and HLA-C homozygous donors in Lithuanians and uses CRISPR-Cas9 to generate synthetic superdonor profiles for regenerative medicine.

This study uses Mendelian randomization to show that genetic risk for mosaic loss of chromosome Y (mLOY) increases AD risk in males, but not females, suggesting mLOY directly contributes to AD pathogenesis.

This paper reports six novel genetic variants associated with Alzheimer's disease risk and demonstrates the utility of polygenic risk scores for risk stratification and age at onset prediction.