Probing the interaction between the WDR41 7CD loop of the C9ORF72 complex and purified PQLC2
Layal Jamal, Philémon von Gaudecker, Laura Pieri, Céline Ransy, Nodoka Nakamae, François André, Igor Tascón, Hanxing Jiang, Borja Ochoa-Lizarralde, Iban Ubarretxena‐Belandia, Cécile Debacker, Bruno Gasnier, Leandro C. Tabares, José Luis Vázquez-Ibar
This study characterizes the interaction between PQLC2 and the WDR41 7CD loop using EPR spectroscopy, revealing structural and dynamic insights into their binding mechanism.
bioRxiv · Sep 22, 2026 · PreprintBiochemistry