BioinformaticsGenome biologyPeer-reviewed
Manifold Alignment Reveals Correspondence Between Single Cell Transcriptome and Epigenome Dynamics
Joshua D. Welch, Alexander J. Hartemink, Jan F. Prins
The paper introduces MATCHER, a method that aligns single cell transcriptomic and epigenomic data to infer shared trajectories, revealing correlations between gene expression and epigenetic changes in mouse embryonic stem cells.
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