Author

Lee McDaniel

Personalis (United States)ORCID 0000-0003-1036-613XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Charles W. AbbottiD· 1 shared Dattatreya MellacheruvuiD· 1 shared Éric Levy· 1 shared Gabor T. Bartha· 1 shared John S. West· 1 shared Michael P. SnyderiD· 1 shared Rachel Marty PykeiD· 1 shared Richard CheniD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioinformatics

Charles W. AbbottORCID

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1 paper

Recent·Most cited

BioinformaticsbioRxivPreprintMay 20, 2021

Validated machine learning algorithm with sub-clonal sensitivity reveals widespread pan-cancer human leukocyte antigen loss of heterozygosity

Rachel Marty Pyke, Dattatreya Mellacheruvu, Steven Dea…·Sean Michael Boyle

The paper develops DASH, a machine learning algorithm to detect HLA LOH in cancer, showing 18% prevalence across 611 patients and correlations with PD-L1 and MSI.

1 citation

humanwhole-exome sequencing

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