Author

John H. Maddocks

École Polytechnique Fédérale de LausanneORCID 0000-0003-1127-8481Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:database / resource· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Daiva Petkevičiūtė-GerlachiD· 2 shared Rahul SharmaiD· 2 shared Alessandro S. Patelli· 1 shared Oscar Gonzalez· 1 shared Rasa GiniūnaitėiD· 1 shared Raushan SinghiD· 1 shared Skirmantas KriaučionisiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 15 mutual co-author links

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2 shared papersBiophysics

Daiva Petkevičiūtė-GerlachORCID

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2 papers

Recent·Most cited

Sequence-dependent conformational and mechanical landscapes of double-stranded nucleic acids

Rahul Sharma, Alessandro S. Patelli, Raushan Singh, Daiva Petkevičiūtė-Gerlach, Oscar Gonzalez, John H. Maddocks

This study introduces cgNA+, a model predicting sequence-dependent mechanical properties of dsNAs with high accuracy, revealing hidden regulatory layers in nucleic acid mechanics.

bioRxiv · Oct 18, 2026 · PreprintBiophysics

Nucleosome wrapping energy in CpG islands and the role of epigenetic base modifications

Rasa Giniūnaitė, Rahul Sharma, John H. Maddocks, Skirmantas Kriaučionis, Daiva Petkevičiūtė-Gerlach

The paper models how CpG island density and epigenetic modifications affect DNA nucleosome wrapping energy and probability.

eLife · May 29, 2024Peer-reviewedBiophysics