Sequence-dependent conformational and mechanical landscapes of double-stranded nucleic acids
Rahul Sharma, Alessandro S. Patelli, Raushan Singh, Daiva Petkevičiūtė-Gerlach, Oscar Gonzalez, John H. Maddocks
This study introduces cgNA+, a model predicting sequence-dependent mechanical properties of dsNAs with high accuracy, revealing hidden regulatory layers in nucleic acid mechanics.
bioRxiv · Oct 18, 2026 · PreprintBiophysics