Systems BiologyPLoS Computational BiologyPeer-reviewed
Population heterogeneity in the epithelial to mesenchymal transition is controlled by NFAT and phosphorylated Sp1
Russell A. Gould, David M. Bassen, Anirikh Chakrabarti…·Jonathan Talbot Butcher
The paper develops a mathematical model of EMT regulation, identifies NFAT and phosphorylated Sp1 as master regulators, and shows that dual TGF-{beta} and VEGF-A exposure leads to phenotypic heterogeneity.
29 citations