Author

Sebastien Baur

Institut PasteurORCID 0000-0003-1228-3039Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Organism:bacteria (other)· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Approach:variational autoencoder· 1

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Alex Hawkins‐HookeriD· 1 shared Arthur Chen· 1 shared David BikardiD· 1 shared Florence DepardieuiD· 1 shared Guillaume CouaironiD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperBioinformatics

Alex Hawkins‐HookerORCID

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1 paper

Recent·Most cited

BioinformaticsPLoS Computational BiologyPeer-reviewedFeb 26, 2021

Generating functional protein variants with variational autoencoders

Alex Hawkins‐Hooker, Florence Depardieu, Sebastien Baur…·David Bikard

This paper uses variational autoencoders to generate functional protein variants of bacterial luciferase, showing high success rates in retaining activity despite significant sequence changes.

211 citationstop 1%

bacteria (other)protein sequence

𝕏 PostBluesky