Author

Philip Arevalo

Wesleyan UniversityORCID 0000-0003-1237-2314Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Organism:bacteria (other)· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:comparative / phylogenetic analysis· 1 Approach:mechanistic / dynamical model· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Aayatti Mallick GuptaiD· 2 shared Erika Anne TayloriD· 2 shared Alex Gorman· 1 shared Bakar A. HassaniD· 1 shared Hamza HabibiD· 1 shared June W. Butelman· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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2 shared papersEvolutionary Biology

Aayatti Mallick GuptaORCID

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2 papers

Recent·Most cited

HepI and OpsX are functionally coupled but evolutionarily asymmetric heptosyltransferase variants: ecological transitions and operon modularization drive divergent constraints and flexibility

Aayatti Mallick Gupta, Philip Arevalo, Erika Anne Taylor

This paper compares HepI and OpsX heptosyltransferases in Gram-negative bacteria, finding they are functionally linked but evolve asymmetrically due to ecological and genomic factors.

bioRxiv · Jun 12, 2026 · PreprintEvolutionary Biology

Structural Adaptations of HepI Enzymes in Proteobacteria: Insights into Evolutionary Resilience and Functional Dynamics

Aayatti Mallick Gupta, Hamza Habib, Bakar A. Hassan, June W. Butelman, Alex Gorman, Philip Arevalo, Erika Anne Taylor

This study identifies sequence motifs in HepI enzymes that correlate with LPS structural features and reveals structural adaptations linked to evolutionary resilience and functional versatility in proteobacteria.

Protein Science · Jan 20, 2026Peer-reviewedEvolutionary Biology