Competitive binding and geometric changes allow fast, complete translocation of intact HIV-1 capsids through the nuclear pore complex
Bhavya Mishra, Roya Zandi, Ajay Gopinathan
This paper develops a biophysical model to explain how HIV-1 capsids translocate through the nuclear pore complex, showing that competitive binding and geometric changes enable fast and complete nuclear import.
bioRxiv · Aug 11, 2025 · PreprintBiophysics