GenomicsbioRxivPreprint
Coessentiality And Cofunctionality: A Network Approach To Learning Genetic Vulnerabilities From Cancer Cell Line Fitness Screens
Traver Hart, Clara WT Koh, Jason Moffat
The paper develops a network approach to identify genetic vulnerabilities in cancer cell lines by analyzing shRNA screens and clustering coessential genes to discover context-specific essential genes and biomarkers.
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