Author

Jeffrey Zhong

Rice UniversityORCID 0000-0003-1431-6973Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:benchmark study· 1 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Assay:GWAS summary statistics· 1 Organism:human· 1

Frequent Co-Authors

Ruth DannenfelseriD· 2 shared Vicky YaoiD· 2 shared Lechuan LiiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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2 shared papersCancer Biology

Ruth DannenfelserORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJun 25, 2026

Alternative splicing reshapes protein interaction networks through structured, directional rewiring across cancers

Jeffrey Zhong, Ruth Dannenfelser, Vicky Yao

The paper analyzes alternative splicing's impact on protein interaction networks across cancers, identifying structured rewiring patterns and their association with patient survival.

DOI 10.64898/2026.06.24.734271

humanbulk RNA-seq

𝕏 PostBluesky

BioinformaticsbioRxivPreprintJan 29, 2025

Benchmarking gene embeddings from sequence, expression, network, and text models for functional prediction tasks

Jeffrey Zhong, Lechuan Li, Ruth Dannenfelser, Vicky Yao

This study benchmarks 38 gene embedding methods across three functional prediction tasks, finding literature-based embeddings perform best overall, while sequence-based models excel in genetic interactions.

6 citations

protein sequenceprotein structure

𝕏 PostBluesky