Multi-scale phase separation by explosive percolation with single chromatin loop resolution
Kaustav Sengupta, Michał Denkiewicz, Mateusz Chiliński, Teresa Szczepińska, Ayatullah Faruk Mollah, Sevastianos Korsak, Raissa M. D’Souza, Yijun Ruan, Dariusz Plewczyński
The paper models chromatin folding using explosive percolation theory and shows that 80% of loops are needed for 3D condensation across cell lines.
Computational and Structural Biotechnology Journal · Jan 1, 2022Peer-reviewedGenomics