Mikhail Burtsev

The paper benchmarks gene annotation methods, showing fine-tuned DNA language models outperform existing tools and generalize across species and annotate non-coding transcripts.

This paper adapts a modernized BERT-style model to genomic sequence modeling, achieving strong efficiency and performance, and releases it as an open baseline.

GENA-LM introduces transformer-based DNA language models for long sequences, capable of handling up to 36,000 base pairs and supporting multispecies and taxon-specific applications.

GENA-Web is a web platform using DNA language models to annotate genomic elements, including promoter activity, splice sites, chromatin features, and enhancer activity in Drosophila.